Director Translational Medicine, R&D Oncology

Full Time
Boston, MA 02210
Posted
Job description

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines for some of the world’s most serious diseases. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations, because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

Be part of fulfilling our ambition to be world leaders in Oncology. We are already the fastest growing team within AstraZeneca and across the industry, and there are countless new indications and targets in our game-changing pipeline. The vision of AstraZeneca Oncology is to redefine cancer, redefine our solutions to cancer, and restore patients' lives. To achieve this, we have an exciting and diverse portfolio that focuses on four scientific platforms that we believe show the greatest potential for yielding effective medicines for cancer patients. A place built on courage, curiosity and collaboration – we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline.

This position can be based in any of these locations of Astrazeneca - Gaithersburg, Maryland, US / Boston, Massachusetts, US / Barcelona, Spain

We are seeking a postdoctoral scientist with a background in biology to join a world class center for discovery and development of innovative cancer medicines. In this role you will be accountable for delivery of robust, scientifically driven biomarkers in drug discovery and development programs for immuno oncology agents. You will be responsible for coordinating and delivering translational science strategies and studies to facilitate clinical evaluation of projects in the portfolio. You will have the opportunity to impact an industry-leading portfolio and provide excellent representation of discovery scientific input to enable successful clinical decisions.

Key Responsibilities and Accountabilities:

  • Through guiding the analysis of patient samples using the best available science and technologies, derive insights that guide indication selection, identify targeted patient populations, support rational drug combinations, and inform mechanisms of resistance.

  • Collaborate with Oncology Research and Clinical Development teams to ensure incorporation of robust biomarker strategies for molecules in all phases of development.

  • Collaborate with clinical teams to implement exploratory sample collection and analyses in clinical studies related to immuno-oncology.

  • Manage internal and external research collaborations in areas of clinical technologies and oncology translational research.

  • Contribute to and ensure the quality of Translational Medicine clinical study reports, data review and interpretation, presentations, scientific publications and recommendations to development teams and management.

Essential Requirements and Qualifications

Education Required:

  • PhD in a scientific discipline relevant to oncology with 1+ years of experience

Experience Required:

  • In-depth knowledge of pathways and biology relevant to immuno-oncology

  • Proven communication, presentation and influencing skills.

  • Highly developed problem solving and risk management skills.

  • Highly developed collaborative working skills.

  • Ability to act as an external ambassador and to influence external organizations to enhance the image and reputation of AstraZeneca.

  • Experience of drug discovery or development and/or exposure to translational research desirable.

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