Department

Lineberger Compr Cancer Center-426801

Career Area

Research Professionals

Posting Open Date

02/24/2023

Application Deadline

04/19/2023

Open Until Filled

No

Position Type

Permanent Staff (EHRA NF)

Working Title

Research Associate

Appointment Type

EHRA Non-Faculty

Position Number

20052373

Vacancy ID

NF0006726

Full Time/Part Time

Full-Time Permanent

FTE

1

Hours per week

40

Position Location

North Carolina, US

Hiring Range

Dependent on Education/Experience

Proposed Start Date

03/20/2023

Primary Purpose of Organizational Unit

The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.
OUR VISION
Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding.
OUR MISSION
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research.
Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.
Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.

Position Summary

Our collaborative and multidisciplinary translational tumor immunology group (https://pirl.unc.edu/) is seeking to hire a research associate who is highly skilled in cytometry and functional analysis of T cells to lead a project discovering tumor antigen-specific T cell receptors and mechanisms of resistance to antigen-specific T cell cytotoxicity in NUT carcinoma. The goal of this research is to develop novel immunotherapies for this cancer which has a poor prognosis and very few if any good therapeutic options. The successful applicant will be able to conceive, plan, and execute experiments independently, as well as to analyze data and lead a small team in executing research goals in collaboration with principal investigators and other lab members. Beyond cytometry and functional T cell studies, experimental work will include single cell transcriptomic and T cell receptor analyses using human cell lines, primary tumor samples, and murine models. There will be substantial interaction with lab members working in bioinformatics and computational biology as well as opportunity for training in these areas if the applicant desires. As part of this work, they will be expected to lead and contribute to academic products including presentations, manuscripts, and patents deriving from their experimental results. If desired, the applicant will have the opportunity to be the lead author on presentations, manuscripts, and grants derived from their work.

Minimum Education and Experience Requirements

Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor’s degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure.

Required Qualifications, Competencies, and Experience

The successful applicant should have at minimum a Bachelor’s degree in immunology (or similar discipline) with relevant experience and documented expertise in leading research projects through to completion. They will also have demonstrated technical excellence in cytometry (flow cytometry and/or mass cytometry) including processing of samples for high-quality cytometry analysis.

Preferred Qualifications, Competencies, and Experience

Preferred qualifications include (1) PhD in immunology, (2) experience with processing samples from both human and murine peripheral blood and tumor tissues, (3) experience with genomics studies and bioinformatics tools to analyze data from these, (4) experience with team leadership and project management in research collaborations.

Special Physical/Mental Requirements

Campus Security Authority Responsibilities