Senior Research Associate/Associate Scientist, Discovery Biology
Full Time
San Francisco, CA
$107,000 - $130,000 a year
Posted
Job description
About BridgeBio Oncology Therapeutics & BridgeBio Pharma
BridgeBio Oncology Therapeutics (“BBOT”) is our team of researchers working to develop novel therapeutics to address dire unmet needs in oncology. Led by top scientists with extensive track records in drug development, like Frank McCormick and Eli Wallace, our team utilizes structure-based drug discovery techniques to target some of oncology’s most challenging and validated molecular targets, including KRAS and PI3Kα. We are focused and committed to patients, scientific excellence, and operational agility, and we understand that every minute counts in our efforts to develop new therapies to transform the lives of people living with cancer. Our main oncology laboratory is located in South San Francisco, though our research collaborators span the country and the globe.
BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.
Our focus on scientific excellence and rapid execution aim to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, Boston, New York, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zug, Switzerland, and are expanding across Europe.
To learn more about our story and company culture, visit us at
https://bridgebio.com
Who You Are
This is an exciting opportunity for a highly motivated Senior Research Associate/Associate Scientist with a strong background in cancer biology to join BridgeBio’s search for innovative cancer therapeutics. We are looking for a talented and enthusiastic individual who thrives in a collaborative, fast-paced, and growing environment to join our team as a laboratory-based leader.
Responsibilities
- Play a critical intellectual and technical role in discovering and developing novel small molecule cancer therapeutics
- Independently design, conduct, and analyze experiments to advance our understanding of cancer biology and propel drug discovery programs across our oncology pipeline
- Execute pharmacology experiments (biochemical and cell-based assays) to assess the inhibition or activation of cell signaling in the oncology setting, including in response to small molecule inhibitors
- Conduct compound screening (including medium- and high-throughput studies) to identify leads and potential combination therapies
- Develop novel tools (such as genetically engineered cell lines) and assays as needed to support the group’s discovery mission
- Communicate your findings across seniority levels within and beyond BridgeBio
- Collaborate closely with colleagues across scientific functions and departments, providing key scientific expertise and guidance in an interdisciplinary environment.
- Provide scientific and technical leadership to junior team members
- Keep complete and timely records in electronic lab notebooks
- Patient Champions, who put patients first and uphold strict ethical standards
- Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
- Truth Seekers, who are detailed, rational, and humble problem solvers
- Individuals Who Inspire Excellence in themselves and those around them
- High-quality executors, who execute against goals and milestones with quality, precision, and speed
No matter your role at BridgeBio, successful team members are:
Education, Experience & Skills Requirements
- SRA: B.A./B.S. + 4 years of experience or M.A./M.S. + 3 years of experience in a relevant discipline (e.g., Cancer Biology, Genetics, Molecular Biology)
- Associate Scientist: M.A./M.S. + 6 years of experience in a relevant discipline or Ph.D. degree in a relevant discipline (e.g., Cancer Biology, Genetics, Molecular Biology)
- Relevant prior research or industry experience in a cell/molecular biology laboratory within an oncology setting
- Broad knowledge of cancer biology and independence in critical thinking and scientific achievement
- Experience with a broad range of cellular and biochemical techniques, including mammalian tumor cell culture and engineering, CRISPR, RNAi, immuno-blotting, NGS, IF/IHC, and FACS
- Research experience in oncology drug discovery project teams, cancer cell-based assay design, and assay development is advantageous
- Strong problem-solving skills and a commitment to continuous learning and development
- Ability to excel in a highly-collaborative and innovative environment
What We Offer
- Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
- A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
- An unyielding commitment to always putting patients first. Learn more about how we do this here
- A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
- A place where you own the vision – both for your program and your own career path
- A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
- Access to learning and development resources to help you get in the best professional shape of your life
- Robust and market competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
- Flexible PTO
- Rapid career advancement for strong performers
- Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
- Partnerships with leading institutions
- Commitment to Diversity, Equity & Inclusion – with initiatives like Women at Bridge, we are committed to fostering an inclusive environment where every person feels seen, valued, and heard
$107,000 - $130,000 a year
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. The anticipated salary range for candidates for this role who will work in California is
$107,000 to $130,000/year. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
We will not accept unsolicited resumes from agencies. Please do not send agency resumes to our website or BridgeBio and affiliating employees.
abouteureka.com is the go-to platform for job seekers looking for the best job postings from around the web. With a focus on quality, the platform guarantees that all job postings are from reliable sources and are up-to-date. It also offers a variety of tools to help users find the perfect job for them, such as searching by location and filtering by industry. Furthermore, abouteureka.com provides helpful resources like resume tips and career advice to give job seekers an edge in their search. With its commitment to quality and user-friendliness, abouteureka.com is the ideal place to find your next job.