Job description
Who Are We?
Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. Instead, we regulate the epigenome to suppress and activate multiple genes simultaneously. We are further evolving the platform and leveraging its strengths to address unmet medical needs.
We are looking for exceptional team members who want an active role in building a rapidly growing biotech.
We are on a mission to help patients regain independence through the thoughtful design of safe and reversible therapeutics. You may be, accurately, wondering "how do you do this"? Well, our team is developing a proprietary technology platform to target various regenerative pathways critical for the establishment of complex diseases.
We are now looking for curious, passionate, and motivated scientists to join an organization developing the new age of regenerative medicine. Besides the research aspects of the job, ask yourself:
- Do you want to be an influential member to an early biotech, where your contributions actually matter? Guess what, you will find that here.
- Looking to advance in your career across non-research function? Learn from experienced team members here.
- Have an interesting idea to add to the company culture? Let's implement it!
We are looking for team members to join ASAP.
Our small but growing team currently operates out of South San Francisco. We are easily accessible from SF, the Peninsula, and the East Bay (for those interested in the occasional ferry rides).
Checklist for successful candidates:
- BS/MS in molecular biology, biotechnology, pharmaceutical, stem cell or related fields, with 3+ years of relevant research experience in industry or academia
- Experience with high-throughput functional CRISPR screening; prior experience using gene editing, RNAi, CRISPRa/i, or CRISPR KO strategies
- Working knowledge of NGS technologies and workflows
- Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results
- Exceptional candidates will also possess the following skills:
- Experience in maintaining cell culture such as HEK293s, T cells or hepatocyte culture
- Experience in PCR/RT-PCR
- Experience in DNA prep (mini and maxi preps, transfection, etc.)
- Experience in molecular cloning (digestion, ligation, Gibson assembly, gel electrophoresis, etc.)
- Experience in lentivirus packaging
- Experience with flow-cytometry
- Single cell RNA-seq a plus
What you will accomplish here:
- Develop the high-throughput screening for a portfolio of cell therapy applications
- Develop DNA constructs and CRISPR libraries
- Develops, evaluates, optimizes and implements new technologies, laboratory protocols, and methodologies for biochemical and cell-based assays
- Provide expert support for multiplexing and scaling biological readouts across our broader scientific team
- Maintain familiarity with the relevant current literature and its application to multiplexing readouts and cell therapy
- Coordinate tasks across multiple projects, demonstrating prioritization and planning
- Interpret and effectively execute experiments in line with project timelines and goals
Compensation: The salary range for this position is $100,000 to $120,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.
This is an exciting opportunity to participate in building a company's science and culture from the ground up, and we look forward to hearing from you!
Epic Bio is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation. Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes.
Epic Bio provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
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